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What is the difference?

Genital herpes vs Cold sores

Cold sores and genital herpes sound like two separate problems, but both are caused by the herpes simplex virus. The difference is mainly where the infection shows up and which type of the virus is most often involved.

General information, not medical advice. For advice about your own situation, talk to a clinician, pharmacist or sexual health clinic.

Genital herpes

Genital herpes is a common, lifelong viral infection caused by the herpes simplex virus, which can cause recurring blisters or sores but often goes unnoticed.

Full entry

Cold sores

Cold sores are small blisters around the lips caused by the herpes simplex virus, most often type 1, and are extremely common.

Full entry

Side by side

Genital herpesCold sores
Where it appearsGenital herpesAround the genitals, anus, thighs or buttocks.Cold soresAround the lips and mouth, sometimes elsewhere on the face.
Usual virus typeGenital herpesMostly HSV-2, though HSV-1 can also cause it, often through oral sex.Cold soresMostly HSV-1.
How it is usually caughtGenital herpesSkin-to-skin contact during vaginal, anal or oral sex.Cold soresOrdinary contact such as kissing, often in childhood.
How commonGenital herpesThe WHO estimates that about 13% of people aged 15 to 49 have HSV-2.Cold soresThe WHO estimates that about 64% of people under 50 have HSV-1.
How it is seenGenital herpesOften treated as an STI and tested for at sexual health clinics.Cold soresUsually seen as an everyday skin condition.

In short

Same virus family, different location. Avoiding kissing and oral sex while a sore is present lowers the chance of passing it on.

What they have in common

Both are lifelong infections that can flare up and settle, both are most contagious from the first tingle until sores heal, and both can be eased with antiviral medicine. A cold sore can pass to a partner's genitals during oral sex.

Sources

  1. WHOHerpes simplex virus fact sheet
  2. NHSCold sores
  3. NHSGenital herpes

More comparisons

Last reviewed 16 October 2026. Spotted a mistake?